The genetics of addictions: uncovering the genes

  title={The genetics of addictions: uncovering the genes},
  author={David Goldman and G{\'a}bor Oroszi and Francesca Ducci},
  journal={Nature Reviews Genetics},
The addictions are common chronic psychiatric diseases that today are prevented and treated using relatively untargeted and only partially effective methods. The addictions are moderately to highly heritable, which is paradoxical because these disorders require use; a choice that is itself modulated by both genes and environment. The addictions are interrelated and related to other psychiatric diseases by common neurobiological pathways, including those that modulate reward, behavioural control… 

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Genetics of addictions: strategies for addressing heterogeneity and polygenicity of substance use disorders

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    Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2008
The European IMAGEN study will be introduced that aims to integrate methodical approaches discussed in order to identify the genetic and neurobiological basis of behavioural traits relevant to the development of addictions by presenting results of recent research on genetic and environmental components of addiction.



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