The genetics of addictions: uncovering the genes

@article{Goldman2005TheGO,
  title={The genetics of addictions: uncovering the genes},
  author={David Goldman and G{\'a}bor Oroszi and Francesca Ducci},
  journal={Nature Reviews Genetics},
  year={2005},
  volume={6},
  pages={521-532}
}
The addictions are common chronic psychiatric diseases that today are prevented and treated using relatively untargeted and only partially effective methods. The addictions are moderately to highly heritable, which is paradoxical because these disorders require use; a choice that is itself modulated by both genes and environment. The addictions are interrelated and related to other psychiatric diseases by common neurobiological pathways, including those that modulate reward, behavioural control… 

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