The genetics of adaptive shape shift in stickleback: pleiotropy and effect size.

@article{Albert2008TheGO,
  title={The genetics of adaptive shape shift in stickleback: pleiotropy and effect size.},
  author={Arianne Y K Albert and Sterling Sawaya and Timothy H. Vines and Anne K. Knecht and Craig T Miller and Brian R. Summers and Sarita Balabhadra and David M. Kingsley and Dolph Schluter},
  journal={Evolution; international journal of organic evolution},
  year={2008},
  volume={62 1},
  pages={76-85}
}
The distribution of effect sizes of genes underlying adaptation is unknown (Orr 2005). Are suites of traits that diverged under natural selection controlled by a few pleiotropic genes of large effect (major genes model), by many independently acting genes of small effect (infinitesimal model), or by a combination, with frequency inversely related to effect size (geometric model)? To address this we carried out a quantitative trait loci (QTL) study of a suite of 54 position traits describing… CONTINUE READING
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