The genetics of Parkinson's disease.

  title={The genetics of Parkinson's disease.},
  author={Lawrence I. Golbe},
  journal={Reviews in the neurosciences},
  volume={4 1},
The possibility of a major contribution of hereditary factors to the cause of Parkinson's disease (PD) is being reconsidered by many. The studies preceding the 1980s presented conflicting evidence and suffered from procedural difficulties. The emergence of the MPTP hypothesis and the failure of three twin studies to document a strong hereditary component in the early 1980s turned attention toward an environmental cause of PD. However more recent descriptions of deficiencies in genetically-coded… CONTINUE READING

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