The genetic variation of lactase persistence alleles in northeast Africa

@article{Hollfelder2020TheGV,
  title={The genetic variation of lactase persistence alleles in northeast Africa},
  author={Nina Hollfelder and Hiba Babiker and Lena Graneh{\"a}ll and Carina M. Schlebusch and Mattias Jakobsson},
  journal={bioRxiv},
  year={2020}
}
Lactase persistence (LP) is a well-studied example of a Mendelian trait under selection in some human groups due to gene-culture co-evolution. We investigated the frequencies of genetic variants linked to LP in Sudanese and South Sudanese populations. These populations have diverse subsistence patterns, and some are dependent on milk to various extents, not only from cows, but also from other livestock such as camels and goats. We sequenced a 316bp region involved in regulating the expression… 
2 Citations

Human adaptation, demography, and cattle domestication: an overview of the complexity of lactase persistence in Africa.

This review summarizes recent advances in the understanding of the genetic basis and evolutionary history of lactase persistence, as well as the factors that influenced the origin and spread of pastoralism in Africa.

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