The genetic program for cartilage development has deep homology within Bilateria

@article{Tarazona2016TheGP,
  title={The genetic program for cartilage development has deep homology within Bilateria},
  author={Oscar A. Tarazona and Leslie A Slota and D. Lopez and Guangjun Zhang and M. Cohn},
  journal={Nature},
  year={2016},
  volume={533},
  pages={86-89}
}
The evolution of novel cell types led to the emergence of new tissues and organs during the diversification of animals. The origin of the chondrocyte, the cell type that synthesizes cartilage matrix, was central to the evolution of the vertebrate endoskeleton. Cartilage-like tissues also exist outside the vertebrates, although their relationship to vertebrate cartilage is enigmatic. Here we show that protostome and deuterostome cartilage share structural and chemical properties, and that the… Expand
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