The genetic influence on bone susceptibility to fluoride.

  title={The genetic influence on bone susceptibility to fluoride.},
  author={Maryline Mousny and Xavier Banse and Lisa M. Wise and Eric T. Everett and Ron Hancock and Reinhold Vieth and J. P. Devogelaer and Marc D. Grynpas},
  volume={39 6},
INTRODUCTION The influence of genetic background on bone architecture and mechanical properties is well established. Nevertheless, to date, only few animal studies explore an underlying genetic basis for extrinsic factors effect such as fluoride effect on bone metabolism. MATERIALS AND METHODS This study assessed the effect of increasing fluoride doses (0 ppm, 25 ppm, 50 ppm, 100 ppm) on the bone properties in 3 inbred mouse strains that demonstrate different susceptibilities to developing… CONTINUE READING

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