The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study.

@article{Cannon1998TheGE,
  title={The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study.},
  author={Tyrone D. Cannon and Jaakko Kaprio and Jan-Erik L{\"o}nnqvist and Manu Huttunen and Markku Koskenvuo},
  journal={Archives of general psychiatry},
  year={1998},
  volume={55 1},
  pages={67-74}
}
BACKGROUND The magnitude of heritability of schizophrenia remains controversial, due in part to limitations of estimates derived from index twin pairs exclusively. We applied structural equation modeling in a total population of twins to determine the significance and magnitudes of the genetic and environmental contributions to schizophrenia. METHODS All monozygotic (1180 male and 1315 female pairs) and same-sex dizygotic (2765 male and 2613 female pairs) twins born from 1940 to 1957 in… CONTINUE READING
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