The genetic basis of long QT and short QT syndromes: A mutation update

@article{Hedley2009TheGB,
  title={The genetic basis of long QT and short QT syndromes: A mutation update},
  author={Paula L. Hedley and Poul J{\o}rgensen and Sarah Schlamowitz and Romilda Wangari and Johanna C. Moolman-Smook and Paul A. Brink and J{\o}rgen K. Kanters and Valerie A. Corfield and Michael Christiansen},
  journal={Human Mutation},
  year={2009},
  volume={30}
}
Long QT and short QT syndromes (LQTS and SQTS) are cardiac repolarization abnormalities that are characterized by length perturbations of the QT interval as measured on electrocardiogram (ECG). Prolonged QT interval and a propensity for ventricular tachycardia of the torsades de pointes (TdP) type are characteristic of LQTS, while SQTS is characterized by shortened QT interval with tall peaked T‐waves and a propensity for atrial fibrillation. Both syndromes represent a high risk for syncope and… Expand
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