The genetic basis of inbreeding depression.

@article{Charlesworth1999TheGB,
  title={The genetic basis of inbreeding depression.},
  author={Brian Charlesworth and Deborah Charlesworth},
  journal={Genetical research},
  year={1999},
  volume={74 3},
  pages={
          329-40
        }
}
Data on the effects of inbreeding on fitness components are reviewed in the light of population genetic models of the possible genetic causes of inbreeding depression. Deleterious mutations probably play a major role in causing inbreeding depression. Putting together the different kinds of quantitative genetic data, it is difficult to account for the very large effects of inbreeding on fitness in Drosophila and outcrossing plants without a significant contribution from variability maintained by… CONTINUE READING
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