The genetic and environmental basis of atopic diseases

@article{Grammatikos2008TheGA,
  title={The genetic and environmental basis of atopic diseases},
  author={Alexandros Grammatikos},
  journal={Annals of Medicine},
  year={2008},
  volume={40},
  pages={482 - 495}
}
The prevalence of atopic diseases has increased abruptly in recent years in most Westernized societies, making the question why this happened the topic of a heated debate. The best paradigm available to date to explain this steep rise, the ‘hygiene hypothesis’, supports that it is the excess ‘cleanliness’ of our environments that has led to the decline in the number of infectious stimuli that are necessary for the proper development of our immune system. Recent findings support that it is the… 

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