The generation of CD8+ T-cell population specific for vaccinia virus epitope involved in the antiviral protection against ectromelia virus challenge.

@article{Gieryska2015TheGO,
  title={The generation of CD8+ T-cell population specific for vaccinia virus epitope involved in the antiviral protection against ectromelia virus challenge.},
  author={Małgorzata M Gieryńska and Lidia Szulc-Dąbrowska and Tomasz Dzieciątkowski and Anna Golke and Ada Schollenberger},
  journal={Pathogens and disease},
  year={2015},
  volume={73 9},
  pages={ftv088}
}
Eradication of smallpox has led to cessation of vaccination programs. This has rendered the human population increasingly susceptible not only to variola virus infection but also to infections with other representatives of Poxviridae family that cause zoonotic variola-like diseases. Thus, new approaches for designing improved vaccine against smallpox are required. Discovering that orthopoxviruses, e.g. variola virus, vaccinia virus, ectromelia virus, share common immunodominant antigen, may… CONTINUE READING
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