Highly Influenced

@article{Hobolth2009TheGS, title={The genealogy, site frequency spectrum and ages of two nested mutant alleles.}, author={Asger Hobolth and Carsten Wiuf}, journal={Theoretical population biology}, year={2009}, volume={75 4}, pages={260-5} }

- Published 2009 in Theoretical population biology
DOI:10.1016/j.tpb.2009.02.001

In this paper we consider the genealogy of two nested mutant alleles, assuming the constant-size neutral coalescent model with infinite sites mutation. We study the conditional genealogy and derive explicit formulas for the joint and marginal site frequency spectra for the double, single and zero mutant allele. In addition, we find the mean ages of the two mutations. We show that the age of the youngest mutation does not depend on the frequency of the single mutant allele and that the frequencyā¦Ā CONTINUE READING