The gene-richest bands of human chromosomes replicate at the onset of the S-phase.

@article{Federico1998TheGB,
  title={The gene-richest bands of human chromosomes replicate at the onset of the S-phase.},
  author={Concetta Federico and Salvatore Saccone and Giorgio Bernardi},
  journal={Cytogenetics and cell genetics},
  year={1998},
  volume={80 1-4},
  pages={83-8}
}
Previous investigations on the correlations between isochore organization and human chromosomal bands have identified three sets of R(everse) bands: H3+, H3* and H3-, endowed with large, moderate, and no detectable amounts of the gene-richest H3 isochores, respectively. In the present work we compared the replication timing of these three sets of bands and showed that the chromosomal bands containing H3 isochores replicate almost entirely (in the case of H3+ bands) or largely (in the case of H3… CONTINUE READING

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