The gene coding for carbamoyl-phosphate synthetase I was formed by fusion of an ancestral glutaminase gene and a synthetase gene.

Abstract

A near full-length cDNA copy of rat carbamoyl-phosphate synthetase I (EC 6.3.4.16) mRNA has been cloned. The cDNA insert in the recombinant plasmid pHN234 is 5.3 kilobases long. Analysis of the sequence coding for carbamoyl-phosphate synthetase I indicates that the gene has arisen from a fusion of two ancestral genes: one homologous to Escherichia coli carA… (More)

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@article{Nyunoya1985TheGC, title={The gene coding for carbamoyl-phosphate synthetase I was formed by fusion of an ancestral glutaminase gene and a synthetase gene.}, author={Hiroshi Nyunoya and Karen E. Broglie and Carol J. Lusty}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1985}, volume={82 8}, pages={2244-6} }