The gene cluster of aureocyclicin 4185: the first cyclic bacteriocin of Staphylococcus aureus.

  title={The gene cluster of aureocyclicin 4185: the first cyclic bacteriocin of Staphylococcus aureus.},
  author={Amina Potter and Hilana Ceotto and Marcus L{\'i}vio Varella Coelho and Allan J. Guimar{\~a}es and M. do C. de F. Bastos},
  volume={160 Pt 5},
Staphylococcus aureus 4185 was previously shown to produce at least two bacteriocins. One of them is encoded by pRJ101. To detect the bacteriocin-encoding gene cluster, an ~9160 kb region of pRJ101 was sequenced. In silico analyses identified 10 genes (aclX, aclB, aclI, aclT, aclC, aclD, aclA, aclF, aclG and aclH) that might be involved in the production of a novel cyclic bacteriocin named aureocyclicin 4185. The organization of these genes was quite similar to that of the gene cluster… 

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