The gastrointestinal stimulus to insulin release. I. Secretin.

@article{Chisholm1969TheGS,
  title={The gastrointestinal stimulus to insulin release. I. Secretin.},
  author={D. Chisholm and J. Young and L. Lazarus},
  journal={The Journal of clinical investigation},
  year={1969},
  volume={48 8},
  pages={
          1453-60
        }
}
The gastrointestinal stimulus to the release of insulin has been investigated in man by the use of a radioimmunoassay for secretin. Serum secretin levels rose rapidly after the oral ingestion of glucose or protein and preceded the elevation of serum insulin. An intravenous infusion of highly purified secretin caused a release of insulin when the serum secretin levels were within the physiological range. Infusion of hydrochloric acid into the duodenum caused an elevation of serum secretin and… Expand
Effects of secretin on insulin secretion and glucose tolerance.
Uniphasic insulin responses to secretin stimulation in man.
Progess report. Is secretin secreted?
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