The future of exogenous surfactant therapy.

  title={The future of exogenous surfactant therapy.},
  author={Douglas F. Willson and Robert H. Notter},
  journal={Respiratory care},
  volume={56 9},
  pages={1369-86; discussion 1386-8}
Since the identification of surfactant deficiency as the putative cause of the infant respiratory distress syndrome (RDS) by Avery and Mead in 1959, our understanding of the role of pulmonary surfactant in respiratory physiology and the pathophysiology of acute lung injury (ALI) has advanced substantially. Surfactant replacement has become routine for the prevention and treatment of infant RDS and other causes of neonatal lung injury. The role of surfactant in lung injury beyond the neonatal… CONTINUE READING


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Neue auffassungen uber einen grundbegriff der atemmechanik. Dieretraktionskraft der lunge, abhangig von der oberflachenspannung in den alveolen

  • K. von Neergaard
  • Z Ges Exp Med
  • 1929
Highly Influential
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