The functions of mucosal T cells in containing the indigenous commensal flora of the intestine

@article{Macpherson2002TheFO,
  title={The functions of mucosal T cells in containing the indigenous commensal flora of the intestine},
  author={Andrew J Macpherson and Marianne M Martinic and Nicola Harris},
  journal={Cellular and Molecular Life Sciences CMLS},
  year={2002},
  volume={59},
  pages={2088-2096}
}
There is an immense load of non-pathogenic commensal bacteria in the distal small intestine and the colon of mammals. The physical barrier that prevents penetration (translocation) of these organisms into the body is a simple epithelium comprised of the single enterocyte/colonocyte cell layer with its overlying mucus. In this review, we discuss the roles of… CONTINUE READING