The functional state of the dopamine receptor in the anterior pituitary is in the high affinity form.

@article{George1985TheFS,
  title={The functional state of the dopamine receptor in the anterior pituitary is in the high affinity form.},
  author={Susan R. George and Miwa Watanabe and Th{\'e}r{\`e}se Di Paolo and Pierre Falardeau and Fernand Labrie and Philip Seeman},
  journal={Endocrinology},
  year={1985},
  volume={117 2},
  pages={
          690-7
        }
}
In order to determine whether the high affinity state or the low affinity state of the dopamine receptor mediated the inhibition of release of PRL by dopamine agonists, a large number of dopaminergic agonists (n = 31) and antagonists (n = 24) were tested for their potencies to inhibit the binding of [3H] spiperone to porcine anterior pituitary tissue, and for their potencies to affect the release of PRL from rat anterior pituitary cells in culture. All agonists (except bromocriptine… CONTINUE READING
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