The functional significance of ventricular geometry for the transition from hypertrophy to cardiac failure. Does a critical degree of structural dilatation exist?

@article{Jacob1998TheFS,
  title={The functional significance of ventricular geometry for the transition from hypertrophy to cardiac failure. Does a critical degree of structural dilatation exist?},
  author={Ruthard Jacob and R. W. G{\"u}lch},
  journal={Basic Research in Cardiology},
  year={1998},
  volume={93},
  pages={423-429}
}
Although it is generally accepted that ventricular geometric configuration plays an important role for manifestation of cardiac pumping failure, the relative significance of structural dilatation vs impaired myocardial performance – and the interaction of these factors – have not been thoroughly addressed. Besides its unfavorable effects on coronary circulation, cardiac energetics, and arrhythmogenesis, structural ventricular dilatation has direct consequences for stroke volume for geometrical… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Cellular mechanisms of burn-related changes in contractility and its prevention by mesenteric lymph ligation.

American journal of physiology. Heart and circulatory physiology • 2007
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 50 references

Alterations of Excitation-Contraction Coupling in the Failing Human Heart

Die Turbulente, Reibungsschicht In Ebener, Strmung Bei Druckabfall
Steinkopff • 1998

Structural and functional properties of the hypertrophied and failing heart

R Jacob, RW Gülch, G Kissling
Altschuld RA (eds) Heart Metabolism in Failure. Advances in Organ • 1998

Cardiomyoplasty as an isolated procedure to treat refractory heart failure.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery • 1997

ACE inhibitors before or after heart failure?

European journal of clinical pharmacology • 1996

Similar Papers

Loading similar papers…