The functional role of long non-coding RNA in human carcinomas
@inproceedings{Gibb2011TheFR,
title={The functional role of long non-coding RNA in human carcinomas},
author={Ewan A. Gibb and C J Brown and Wan L. Lam},
booktitle={Molecular Cancer},
year={2011}
}
Long non-coding RNAs (lncRNAs) are emerging as new players in the cancer paradigm demonstrating potential roles in both oncogenic and tumor suppressive pathways. These novel genes are frequently aberrantly expressed in a variety of human cancers, however the biological functions of the vast majority remain unknown. Recently, evidence has begun to accumulate describing the molecular mechanisms by which these RNA species function, providing insight into the functional roles they may play in… CONTINUE READING