The functional MICA-129 polymorphism is associated with skin but not joint manifestations of psoriatic disease independently of HLA-B and HLA-C.

@article{Pollock2013TheFM,
  title={The functional MICA-129 polymorphism is associated with skin but not joint manifestations of psoriatic disease independently of HLA-B and HLA-C.},
  author={Remy A. Pollock and Vinod Kumar Mozhikunnam Chandran and Fawnda J Pellett and Arane Thavaneswaran and Lihi Eder and Jenny Barrett and Proton Rahman and Vern T. Farewell and Dafna D Gladman},
  journal={Tissue antigens},
  year={2013},
  volume={82 1},
  pages={43-7}
}
A methionine/valine polymorphism at amino acid 129 of the major histocompatibility complex class I chain-related gene A (MICA-129) categorizes alleles into strong and weak binders of the natural killer (NK) and T-cell receptor NKG2D. We investigated whether MICA-129 is differentially associated with skin and joint manifestations of psoriatic disease (PsD… CONTINUE READING