The functional GRM3 Kozak sequence variant rs148754219 affects the risk of schizophrenia and alcohol dependence as well as bipolar disorder

@article{OBrien2014TheFG,
  title={The functional GRM3 Kozak sequence variant rs148754219 affects the risk of schizophrenia and alcohol dependence as well as bipolar disorder},
  author={N. O'Brien and M. Way and R. Kandaswamy and A. Fiorentino and S. Sharp and Giorgia Quadri and J. Alex and A. Anjorin and D. Ball and Raquin Cherian and K. Dar and A. Gormez and I. Guerrini and M. Heydtmann and A. Hillman and S. Lankappa and Greg Lydall and A. O’Kane and S. Patel and D. Quested and I. Smith and A. Thomson and N. Bass and M. Morgan and D. Curtis and A. McQuillin},
  journal={Psychiatric Genetics},
  year={2014},
  volume={24},
  pages={277 - 278}
}
We previously reported that a Kozak sequence variant in the metabotropic glutamate receptor 3 gene (GRM3), rs148754219, is associated with bipolar disorder (BP) and affects gene transcription and translation (Kandaswamy et al., 2013). A marker near GRM3, rs12704290, is one of the top hits and reached genome-wide significance in a recently reported genome-wide association study of schizophrenia (SZ) (Ripke et al., 2014), and markers for GRM3 have also been reported to demonstrate association… Expand
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