The function of the nuclear receptor peroxisome proliferator-activated receptor delta in energy homeostasis.

@article{Wolf2003TheFO,
  title={The function of the nuclear receptor peroxisome proliferator-activated receptor delta in energy homeostasis.},
  author={George Wolf},
  journal={Nutrition reviews},
  year={2003},
  volume={61 11},
  pages={
          387-90
        }
}
  • G. Wolf
  • Published 1 November 2003
  • Biology
  • Nutrition reviews
The metabolic function of the nuclear receptor peroxisome proliferator-activated receptor delta (PPAR(delta)) has been established by transfer of the PPAR(delta) gene into adipose tissue of mice in vivo and into adipocytes in culture. Investigators found that PPAR(delta) activation by such transfer leads to up-regulation of energy expenditure by fatty acid oxidation. PPAR(delta) activation also results in lowered serum triglyceride and free fatty acid levels and decreased lipid accumulation. In… 

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