The function of natural killer cells: education, reminders and some good memories.


The effector response of natural killer (NK) cells is determined by opposing signals received through activating and inhibitory receptors. A process termed NK cell education, which is guided by the recognition of Major Histocompatibility Complex class I (MHC-I) molecules, determines how efficiently activating receptors respond to stimulation. This ensures… (More)
DOI: 10.1016/j.coi.2010.11.008