The function of leptin in nutrition, weight, and physiology.

Abstract

Recent advances indicate that a robust physiologic system acts to maintain relative constancy of weight in mammals. A key component of this system is leptin. Leptin is an adipocyte hormone that functions as the afferent signal in a negative feedback loop regulating body weight. In addition, leptin functions as a key link between nutrition and the function… (More)

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Cite this paper

@article{Friedman2002TheFO, title={The function of leptin in nutrition, weight, and physiology.}, author={Jeffrey M. Friedman}, journal={Nutrition reviews}, year={2002}, volume={60 10 Pt 2}, pages={S1-14; discussion S68-84, 85-7} }