The function of communities in protein interaction networks at multiple scales

@inproceedings{Lewis2010TheFO,
  title={The function of communities in protein interaction networks at multiple scales},
  author={Anna C. F. Lewis and Nick S. Jones and Mason A. Porter and Charlotte M. Deane},
  booktitle={BMC Systems Biology},
  year={2010}
}
If biology is modular then clusters, or communities, of proteins derived using only protein interaction network structure should define protein modules with similar biological roles. We investigate the link between biological modules and network communities in yeast and its relationship to the scale at which we probe the network. Our results demonstrate that the functional homogeneity of communities depends on the scale selected, and that almost all proteins lie in a functionally homogeneous… CONTINUE READING
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