The function of acyl-CoA-binding protein (ACBP)/Diazepam binding inhibitor (DBI)

  title={The function of acyl-CoA-binding protein (ACBP)/Diazepam binding inhibitor (DBI)},
  author={Jens Knudsen and S Mandrup and Jan Trige Rasmussen and Per Hove Andreasen and Flemming M. Poulsen and Karsten Kristiansen},
  journal={Molecular and Cellular Biochemistry},
Acyl-CoA-binding protein has been isolated independently by five different groups based on its ability to (1) displace diazepam from the GABAA receptor, (2) affect cell growth, (3) induce medium-chain acyl-CoA-ester synthesis, (4) stimulate steroid hormone synthesis, and (5) affect glucose-induced insulin secretion. In this survey evidence is presented to show that ACBP is able to act as an intracellular acyl-CoA transporter and acyl-CoA pool former. The rat ACBP genomic gene consists of 4… CONTINUE READING