The function and the role of the mitochondrial glycerol-3-phosphate dehydrogenase in mammalian tissues.

@article{Mracek2013TheFA,
  title={The function and the role of the mitochondrial glycerol-3-phosphate dehydrogenase in mammalian tissues.},
  author={Tomas Mracek and Zdeněk Drahota and Josef Hou{\vs}těk},
  journal={Biochimica et biophysica acta},
  year={2013},
  volume={1827 3},
  pages={
          401-10
        }
}
Mitochondrial glycerol-3-phosphate dehydrogenase (mGPDH) is not included in the traditional textbook schemes of the respiratory chain, reflecting the fact that it is a non-standard, tissue-specific component of mammalian mitochondria. But despite its very simple structure, mGPDH is a very important enzyme of intermediary metabolism and as a component of glycerophosphate shuttle it functions at the crossroads of glycolysis, oxidative phosphorylation and fatty acid metabolism. In this review we… CONTINUE READING
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