The ftsH gene of Bacillus subtilis is involved in major cellular processes such as sporulation, stress adaptation and secretion.

@article{Deuerling1997TheFG,
  title={The ftsH gene of Bacillus subtilis is involved in major cellular processes such as sporulation, stress adaptation and secretion.},
  author={Elke Deuerling and Axel Mogk and Claus-Peter Richter and Mary Purucker and Wolfgang Schumann},
  journal={Molecular microbiology},
  year={1997},
  volume={23 5},
  pages={921-33}
}
The ftsH gene of Bacillus subtilis has been identified as a general stress gene which is transiently induced after thermal or osmotic upshift. The FtsH protein exhibits 70.1% homology to FtsH of Escherichia coli which constitutes an essential ATP- and Zn(2+)-dependent protease anchored in the cytoplasmic membrane via two N-terminal transmembrane domains. This paper describes the isolation and functional characterization of an ftsH null mutant which was obtained by integration of a cat-cassette… CONTINUE READING