The frizzled/stan pathway and planar cell polarity in the Drosophila wing.

@article{Adler2012TheFP,
  title={The frizzled/stan pathway and planar cell polarity in the Drosophila wing.},
  author={Paul N Adler},
  journal={Current topics in developmental biology},
  year={2012},
  volume={101},
  pages={1-31}
}
Drosophila has been the key model system for studies on planar cell polarity (PCP). The rich morphology of the insect exoskeleton contains many structures that display PCP. Among these are the trichomes (cuticular hairs) that cover much of the exoskeleton, sensory bristles, and ommatidia. Many genes have been identified that must function for the development of normal PCP. Among these are the genes that comprise the frizzled/starry night (fz/stan) and dachsous/fat pathways. The mechanisms that… CONTINUE READING

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