The frequency among Japanese of heterozygotes for deficiency variants of 11 enzymes.

@article{Satoh1983TheFA,
  title={The frequency among Japanese of heterozygotes for deficiency variants of 11 enzymes.},
  author={Chiyoko Satoh and James V. Neel and Akio Yamashita and Kazuaki Goriki and Masaki Fujita and Howard B. Hamilton},
  journal={American journal of human genetics},
  year={1983},
  volume={35 4},
  pages={
          656-74
        }
}
Eleven human enzymes, chosen for this study because of relatively small coefficients of variation for mean activity, have been surveyed for the frequency with which activities less than or equal to 66% of the mean value occur. This criterion should detect almost all heterozygotes for variants lacking any activity plus a fraction of the persons with variants characterized by markedly depressed activity and/or instability. The enzymes surveyed are TPI, PGK, AK1, LDH, GAPD, GPI, PK, 6PGD, G6PD… CONTINUE READING

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