The freeze-dried preservation of liposome encapsulated hemoglobin: a potential blood substitute.

@article{Rudolph1988TheFP,
  title={The freeze-dried preservation of liposome encapsulated hemoglobin: a potential blood substitute.},
  author={Alan S. Rudolph},
  journal={Cryobiology},
  year={1988},
  volume={25 4},
  pages={277-84}
}
In this report, the ability of carbohydrates (trehalose, sucrose, and glucose) to preserve the blood substitute liposome-encapsulated hemoglobin (LEH) in the freeze-dried state is examined. The water-free stabilization of individual components of this blood substitute and LEH is reported. Lyophilization of hemoglobin solutions in the absence of… CONTINUE READING