The free radical theory of aging matures.

@article{Beckman1998TheFR,
  title={The free radical theory of aging matures.},
  author={Kenneth Beckman and Bruce N. Ames},
  journal={Physiological reviews},
  year={1998},
  volume={78 2},
  pages={547-81}
}
The free radical theory of aging, conceived in 1956, has turned 40 and is rapidly attracting the interest of the mainstream of biological research. From its origins in radiation biology, through a decade or so of dormancy and two decades of steady phenomenological research, it has attracted an increasing number of scientists from an expanding circle of fields. During the past decade, several lines of evidence have convinced a number of scientists that oxidants play an important role in aging… CONTINUE READING
Highly Influential
This paper has highly influenced 75 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
1,094 Citations
138 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 1,094 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 138 references

The Free Radical Theory of Aging Matures

  • Bruce N. Ames
  • Physiol . Rev .
  • 1998

Age-related changes in oxidized proteins

  • E. R. STADTMAN
  • J. Biol. Cancer Lett. 114:
  • 1997

Biochemical changes associated accumulation in Alzheimer disease is a source of redoxgeneratedwith the mechanism controlling superoxide radical formation in free radicals

  • L. M. SAYRE, M. SAWADA, AND J. C. CARLSON.
  • Proc . Natl . Acad . Sci . USA
  • 1997

Mitochondrial DNA alterations as agingassociated mo348

  • Y. H. WEI
  • 1997

Similar Papers

Loading similar papers…