The fractionated response of mouse stroma after X-rays and neutrons: influence of early vs late expression of damage.

@article{Hill1989TheFR,
  title={The fractionated response of mouse stroma after X-rays and neutrons: influence of early vs late expression of damage.},
  author={Sally A. Hill and Ken A. Smith and Karen B. Williams and Juliana Denekamp},
  journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology},
  year={1989},
  volume={16 2},
  pages={129-37}
}
The sparing effect of dividing a radiation treatment into many small fractions is different for acutely responding tissues and those which have delayed expression of injury. We have used the Tumour Bed Effect assay (TBE) to investigate the influence of the time of damage expression on the response of the normally quiescent subcutaneous stroma. Implanted tumour cells provide an angiogenic stimulus which forces the vasculature to proliferate. The subcutaneous stroma of the mouse dorsum was… CONTINUE READING