Corpus ID: 27812521

The formation of lipid-linked oligosaccharides in Madin-Darby canine kidney cells. Changes in oligosaccharide profiles induced by glucosamine.

@article{Pan1982TheFO,
  title={The formation of lipid-linked oligosaccharides in Madin-Darby canine kidney cells. Changes in oligosaccharide profiles induced by glucosamine.},
  author={Yuan T. Pan and Alan David Elbein},
  journal={The Journal of biological chemistry},
  year={1982},
  volume={257 6},
  pages={
          2795-801
        }
}
  • Yuan T. Pan, Alan David Elbein
  • Published 1982
  • Chemistry, Medicine
  • The Journal of biological chemistry
  • Glucosamine inhibits the incorporation of [2-3H]mannose into lipid-linked oligosaccharides and into glycoproteins in influenza virus-infected MDCK cells. Fifty per cent inhibition of these components requires about 2 mM glucosamine. The oligosaccharide portions of the lipid-linked oligosaccharides in cells inhibited with glucosamine were compared to that of normal cells by chromatography on Bio-Gel P-4 columns. In uninhibited cells, the major oligosaccharide formed from [2-3H]mannose was the… CONTINUE READING

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