The formation of chemical synapses between cell-cultured neuronal somata.

  title={The formation of chemical synapses between cell-cultured neuronal somata.},
  author={Philip Haydon},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  volume={8 3},
  • Philip Haydon
  • Published 1988 in
    The Journal of neuroscience : the official…
The study of the development and plasticity of chemical synaptic connections is frequently restricted by the lack of access to the synaptic terminals. This can, in part, be overcome by plating neurons into cell culture where all regions of a neuron are made experimentally accessible. However, the small size of synaptic terminals still makes direct experimental manipulation difficult. In this study we have found in the absence of neurite extension, directly contacting cell somata (diameter 50… CONTINUE READING


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