The formation and metabolism of N-hydroxymethyl compounds--IX. N-(acetoxymethyl)-4-chlorobenzamide: an electrophile but not a mutagen in Salmonella typhimurium.

@article{Overton1986TheFA,
  title={The formation and metabolism of N-hydroxymethyl compounds--IX. N-(acetoxymethyl)-4-chlorobenzamide: an electrophile but not a mutagen in Salmonella typhimurium.},
  author={Matthew Overton and Michael D. Threadgill and James Kevin Chipman and Andreas J. Gescher and John A. Hickman},
  journal={Biochemical pharmacology},
  year={1986},
  volume={35 23},
  pages={
          4161-5
        }
}
The metabolism of the 5HT3 antagonists ondansetron, alosetron and GR87442 I: A comparison of in vitro and in vivo metabolism and in vitro enzyme kinetics in rat, dog and human hepatocytes, microsomes and recombinant human enzymes
TLDR
Data support the use of rat, dog and human hepatocytes for the prediction of in vivo metabolites of ondansetron, alosetron and GR87442, and the pharmacokinetics of the three 5HT3 antagonists investigated were dominated by CYP3A4 (and/or 2C9) compared with CYP1A2 in man.

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The formation and metabolism of N-hydroxymethyl compounds. Part 6. The synthesis of S-amidomethyl-, S-ureidomethyl-, and S-(1,3,5-triazin-2-ylaminomethyl)-glutathione derivatives
Treatment of N-hydroxymethyl and N-alkoxymethyl compounds with glutathione or N-acetylcysteine in trifluoroacetic acid affords the corresponding glutathione or N-acetylcysteine derivatives in high
Syntheses of 2-acylaminoacetamidine and 3-acylaminopropionamidine derivatives.
TLDR
3-(p-methyl) benzamidopropionamidine hydrochloride was found to have an inhibitory effect on influenza virus in mice and in membrane culture.
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