The formalin test: scoring properties of the first and second phases of the pain response in rats

@article{Abbott1995TheFT,
  title={The formalin test: scoring properties of the first and second phases of the pain response in rats},
  author={F. Abbott and K. Franklin and R. F. Westbrook},
  journal={Pain},
  year={1995},
  volume={60},
  pages={91-102}
}
  • F. Abbott, K. Franklin, R. F. Westbrook
  • Published 1995
  • Medicine
  • Pain
  • &NA; The formalin test is increasingly used as a model of injury‐produced pain but there is no generally accepted method of pain rating. To examine the properties of various pain rating methods we established dose‐response relations for formalin injected in the plantar surface of one hind paw, and the analgesic effects of morphine and amphetamine using the most frequently reported behavioural measures of pain (favouring, lifting, licking and flinching/shaking of the injured paw) and… CONTINUE READING
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    References

    SHOWING 1-10 OF 65 REFERENCES
    The formalin test in mice: dissociation between inflammatory and non-inflammatory pain
    • 1,883
    Methodological refinements to the mouse paw formalin test. An animal model of tonic pain.
    • 205
    The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats
    • 2,308
    • Highly Influential
    The behavioral response to formalin in preweanling rats
    • 119