The formalin test: scoring properties of the first and second phases of the pain response in rats

  title={The formalin test: scoring properties of the first and second phases of the pain response in rats},
  author={F. Abbott and K. Franklin and R. F. Westbrook},
  • F. Abbott, K. Franklin, R. F. Westbrook
  • Published 1995
  • Medicine
  • Pain
  • &NA; The formalin test is increasingly used as a model of injury‐produced pain but there is no generally accepted method of pain rating. To examine the properties of various pain rating methods we established dose‐response relations for formalin injected in the plantar surface of one hind paw, and the analgesic effects of morphine and amphetamine using the most frequently reported behavioural measures of pain (favouring, lifting, licking and flinching/shaking of the injured paw) and… CONTINUE READING
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