The forkhead transcription factor FoxY regulates Nanos.

  title={The forkhead transcription factor FoxY regulates Nanos.},
  author={Jia L Song and Gary M Wessel},
  journal={Molecular reproduction and development},
  volume={79 10},
FoxY is a member of the forkhead transcription factor family that appeared enriched in the presumptive germ line of sea urchins (Ransick et al. Dev Biol 2002;246:132). Here, we test the hypothesis that FoxY is involved in germ line determination in this animal. We found two splice forms of FoxY that share the same DNA-binding domain, but vary in the carboxy-terminal trans-activation/repression domain. Both forms of the FoxY protein are present in the egg and in the early embryo, and their mRNAs… CONTINUE READING
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