The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.

@article{Yokomine2010TheFB,
  title={The forkhead box M1 transcription factor as a candidate of target for anti-cancer immunotherapy.},
  author={Kazunori Yokomine and Satoru Senju and Tetsuya Nakatsura and Atsushi Irie and Yuki Hayashida and Yoshiaki Ikuta and Michiko Harao and Katsunori Imai and Hideo Baba and Hirotaka Iwase and Hiroaki Nomori and Koji Takahashi and Yataro Daigo and Takuya Tsunoda and Yusuke Nakamura and Yutaka Sasaki and Yasuharu Nishimura},
  journal={International journal of cancer},
  year={2010},
  volume={126 9},
  pages={2153-63}
}
The present study attempted to identify a target antigen for immunotherapy for cholangiocarcinoma. Forkhead box M1 (FOXM1) was selected as a candidate antigen based on the data of previous cDNA microarray analysis of clinical samples of cholangiocarcinoma. The level of FOXM1 mRNA was more than 4 times higher in cancer cells in comparison to adjacent normal… CONTINUE READING