The flexibility of locally melted DNA

  title={The flexibility of locally melted DNA},
  author={Robert A. Forties and Ralf Bundschuh and Michael Guy Poirier},
  booktitle={Nucleic acids research},
Protein-bound duplex DNA is often bent or kinked. Yet, quantification of intrinsic DNA bending that might lead to such protein interactions remains enigmatic. DNA cyclization experiments have indicated that DNA may form sharp bends more easily than predicted by the established worm-like chain (WLC) model. One proposed explanation suggests that local melting… CONTINUE READING