The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines.

@article{Li2000TheFB,
  title={The flavonoid baicalin exhibits anti-inflammatory activity by binding to chemokines.},
  author={Bao Qin Li and Tao Fu and Wang Hua Gong and Nicola Dunlop and H Kung and Yan Yan and Ju-Hee Kang and Ji ming Wang},
  journal={Immunopharmacology},
  year={2000},
  volume={49 3},
  pages={295-306}
}
Baicalin (BA) is a flavonoid compound purified from the medicinal plant Scutellaria baicalensis Georgi and has been reported to possess anti-inflammatory and anti-viral activities. In order to elucidate the mechanism(s) of action of BA, we tested whether BA could interfere with chemokines or chemokine receptors, which are critical mediators of inflammation and infection. We observed that BA inhibited the binding of a number of chemokines to human leukocytes or cells transfected to express… CONTINUE READING
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