The flavone eupatilin inhibits eotaxin expression in an NF-κB-dependent and STAT6-independent manner.


The CC chemokine eotaxin contributes to epithelium-induced inflammation in airway diseases such as asthma. Eupatilin (5,7-dihydroxy-3',4',6'-trimethoxyflavone), a bioactive component of Artemisia asiatica Nakai (Asteraceae), is reported to inhibit the adhesion of eosinophils to bronchial epithelial cells. However, little is known about the molecular… (More)
DOI: 10.1111/sji.12263


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