The fission yeast homologue of CENP-B, Abp1, regulates directionality of mating-type switching.

@article{AguilarArnal2008TheFY,
  title={The fission yeast homologue of CENP-B, Abp1, regulates directionality of mating-type switching.},
  author={Lorena Aguilar-Arnal and Francesc-Xavier Marsellach and Fernando L{\'o}pez Azor{\'i}n},
  journal={The EMBO journal},
  year={2008},
  volume={27 7},
  pages={
          1029-38
        }
}
In fission yeast, mating-type switching involves replacing genetic information contained at the expressed mat1 locus by that of either the mat2P or mat3M donor loci. Donor selection is nonrandom, as mat1P cells preferentially use mat3M for switching, whereas mat1M cells use mat2P. Switching directionality is determined by the cell-type-specific distribution of the Swi2-Swi5 complex that, in mat1P cells, localises to mat3M and, only in mat1M cells, spreads to mat2P in a heterochromatin-dependent… CONTINUE READING
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