The first synthesis and antifungal activities of 9-methoxystrobilurin-type beta-substituted beta-methoxyacrylate.

Abstract

The first synthesis of 9-methoxystrobilurin-type beta-substituted MOAs was successfully achieved. A chiral oudemansin-type beta-substituted MOA was also synthesized utilizing Mukaiyama's asymmetric aldol reaction. Antifungal activities of the synthesized compounds against several representative fungi were examined by disk-diffusion assay. As a result… (More)

Topics

Cite this paper

@article{Uchiro2002TheFS, title={The first synthesis and antifungal activities of 9-methoxystrobilurin-type beta-substituted beta-methoxyacrylate.}, author={Hiromi Uchiro and Koh Nagasawa and Tomoya Kotake and Daiju Hasegawa and Aya Tomita and Susumu Kobayashi}, journal={Bioorganic & medicinal chemistry letters}, year={2002}, volume={12 20}, pages={2821-4} }