The first report on flavonoid isolation from Annona crassiflora Mart.


Annona crassiflora, a native tree from Brazilian Cerrado, is reported to possess several ethnomedical uses. Here, we report the isolation and unambiguous characterisation of the flavonoids quercetin-3-O-β-D-glucopyranosil(1 → 6)-O-α-L-arabinoside (1), known as peltatoside, kaempferol-3-O-β-D-galactopyranoside (2), quercetin-3-O-β-D-galactopyranoside (3), quercetin-3-O-β-L-arabinopiranoside (4) and the ( - )-epicatechin (5) from the hydroalcoholic portion of the leaf ethanolic extract. Their structures were elucidated by using 1D and 2D NMR, ESI-MS, UV/Vis spectroscopy, optical rotation analysis and literature data comparison. The leaf ethanolic extract and its isolated compounds were evaluated by using antimicrobial, antioxidant and larvicidal assays, expressing antimicrobial and antioxidant activities. This is the first report on flavonoid isolation from A. crassiflora.

DOI: 10.1080/14786419.2014.885518

Cite this paper

@article{Lage2014TheFR, title={The first report on flavonoid isolation from Annona crassiflora Mart.}, author={Gisele Avelar Lage and Felipe da Silva Medeiros and Wer{\^o}nica de Lima Furtado and Jacqueline Aparecida Takahashi and Jos{\'e} Dias de Souza Filho and L{\'u}cia Pinheiro Santos Pimenta}, journal={Natural product research}, year={2014}, volume={28 11}, pages={808-11} }