The first recorded outbreak of cryptosporidiosis due to Cryptosporidium cuniculus (formerly rabbit genotype), following a water quality incident.

@article{Puleston2014TheFR,
  title={The first recorded outbreak of cryptosporidiosis due to Cryptosporidium cuniculus (formerly rabbit genotype), following a water quality incident.},
  author={Richard L Puleston and C. Mallaghan and Deborah E. Modha and Paul R. Hunter and Jonathan S. Nguyen-Van-Tam and Christopher M. Regan and G Nichols and Rachel M. Chalmers},
  journal={Journal of water and health},
  year={2014},
  volume={12 1},
  pages={
          41-50
        }
}
We report the first identified outbreak of cryptosporidiosis with Cryptosporidium cuniculus following a water quality incident in Northamptonshire, UK. A standardised, enhanced Cryptosporidium exposure questionnaire was administered to all cases of cryptosporidiosis after the incident. Stool samples, water testing, microscopy slides and rabbit gut contents positive for Cryptosporidium were typed at the Cryptosporidium Reference Unit, Singleton Hospital, Swansea. Twenty-three people were… 
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References

SHOWING 1-10 OF 42 REFERENCES

Long-term Cryptosporidium typing reveals the aetiology and species-specific epidemiology of human cryptosporidiosis in England and Wales, 2000 to 2003.

The findings suggest that national surveillance for Cryptosporidium should be conducted at the species level and Typing of isolates allowed outbreaks to be more clearly delineated, and demonstrated anthroponotic spread of C. parvum as well as C. hominis.

Cryptosporidium Oocysts in a Water Supply Associated with a Cryptosporidiosis Outbreak

An outbreak of cryptosporidiosis occurred in and around Clitheroe, Lancashire, in northwest England, during March 2000 and hydrodynamic modeling was used to give a good estimate of the peak oocyst count at the time of the contamination incident.

Large community outbreak of cryptosporidiosis due to contamination of a filtered public water supply.

Current standards for the treatment of public water supplies may not prevent the contamination of drinking water by Cryptosporidium, with consequent outbreaks of cryptosporidiosis, it is concluded.

Cryptosporidium surveillance and risk factors in the United States.

Cryptosporidiosis in Washington State: an outbreak associated with well water.

It is demonstrated that even underground water systems are vulnerable to contamination, as Presumptive Cryptosporidium oocysts were found in well water and in treated wastewater.

A massive outbreak in Milwaukee of cryptosporidium infection transmitted through the public water supply.

This massive outbreak of watery diarrhea among the residents of Milwaukee was caused by cryptosporidium oocysts that passed through the filtration system of one of the city's water-treatment plants, and water-quality standards and the testing of patients for cryptOSporidium were not adequate to detect this outbreak.

CRYPTOSPORIDIOSIS

Value of syndromic surveillance in monitoring a focal waterborne outbreak due to an unusual Cryptosporidium genotype in Northamptonshire, United Kingdom, June - July 2008.

  • S. SmithA. Elliot G. Smith
  • Medicine
    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
  • 2010
The Cryptosporidium contamination incident described demonstrates the potential usefulness of this information, as it is unusual for syndromic surveillance systems to be able to help monitor such a small-scale outbreak.

The epidemiology of sporadic human infections with unusual cryptosporidia detected during routine typing in England and Wales, 2000–2008

Routine typing of isolates from human cryptosporidiosis cases between 2000 and 2008 revealed that 7439 (51·4%) were Cryptosporidium (C.) hominis, 6372 (44·0%) C. parvum, 443 (3·2%) were not typable and 164 (1·1%) were other Cryptosporaidium species or genotypes.

The infectivity of Cryptosporidium parvum in healthy volunteers.

In healthy adults with no serologic evidence of past infection with C. parvum, a low dose of C.Parvum oocysts is sufficient to cause infection, and there were no secondary cases of diarrhea among household contacts.