The first discovered water channel protein, later called aquaporin 1: molecular characteristics, functions and medical implications.

@article{Benga2012TheFD,
  title={The first discovered water channel protein, later called aquaporin 1: molecular characteristics, functions and medical implications.},
  author={Gheorghe Benga},
  journal={Molecular aspects of medicine},
  year={2012},
  volume={33 5-6},
  pages={
          518-34
        }
}
After a decade of work on the water permeability of red blood cells (RBC) Benga group in Cluj-Napoca, Romania, discovered in 1985 the first water channel protein in the RBC membrane. The discovery was reported in publications in 1986 and reviewed in subsequent years. The same protein was purified by chance by Agre group in Baltimore, USA, in 1988, who called in 1991 the protein CHIP28 (CHannel forming Integral membrane Protein of 28 kDa), suggesting that it may play a role in linkage of the… CONTINUE READING
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