The first acidobacterial laccase-like multicopper oxidase revealed by metagenomics shows high salt and thermo-tolerance

@article{Ausec2017TheFA,
  title={The first acidobacterial laccase-like multicopper oxidase revealed by metagenomics shows high salt and thermo-tolerance},
  author={Luka Ausec and Francesca Berini and Carmine Casciello and Mariana Silvia Cretoiu and Jan Dirk van Elsas and Flavia Marinelli and Ines Mandic-Mulec},
  journal={Applied Microbiology and Biotechnology},
  year={2017},
  volume={101},
  pages={6261-6276}
}
Metagenomics is a powerful tool that allows identifying enzymes with novel properties from the unculturable component of microbiomes. However, thus far only a limited number of laccase or laccase -like enzymes identified through metagenomics has been subsequently biochemically characterized. This work describes the successful bio-mining of bacterial laccase-like enzymes in an acidic bog soil metagenome and the characterization of the first acidobacterial laccase-like multicopper oxidase (LMCO… CONTINUE READING
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